Colloidal Silicon Dioxide

Premium pharmaceutical grade colloidal silicon dioxide with excellent glidant and anti-caking properties for improved powder flow and processing.

Colloidal Silicon Dioxide

Product Overview

Colloidal Silicon Dioxide is a submicroscopic fumed silica with a three-dimensional structure. It is widely used as a glidant and anti-caking agent in pharmaceutical formulations to improve powder flow properties and prevent agglomeration during processing and storage.

Key Features

  • Excellent glidant properties
  • Superior anti-caking effect
  • High surface area
  • Chemically inert
  • Low usage concentration
  • Regulatory compliant

Technical Specifications

AppearanceWhite, fluffy powder
Primary Particle Size5-50 nm
Specific Surface Area200 ± 25 m²/g
Moisture Content≤ 2.0%
Bulk Density0.03-0.06 g/cm³
Tapped Density0.05-0.10 g/cm³
SolubilityInsoluble in water and organic solvents

Silicon Dioxide (SiO₂)≥ 99.8%
pH (4% suspension)3.7 - 4.7
Loss on Drying≤ 2.0%
Loss on Ignition≤ 2.0%
Heavy Metals≤ 10 ppm
Lead≤ 2 ppm
Arsenic≤ 2 ppm

Total Aerobic Count≤ 100 CFU/g
Yeast & Mold≤ 10 CFU/g
E. coliAbsent/g
SalmonellaAbsent/25g
S. aureusAbsent/g
P. aeruginosaAbsent/g

Applications

Glidant

Improves powder flow properties in tablet formulations.

Anti-caking Agent

Prevents powder agglomeration during storage.

Tablet Manufacturing

Essential in direct compression and wet granulation.

Capsule Filling

Improves flow properties for capsule filling operations.

Powder Blends

Prevents segregation in powder blends.

Food Applications

Used as anti-caking agent in food products.

Regulatory Compliance

IP
BP
USP
Ph.Eur

Certifications

ISO 9001
ISO 14001
ISO 45001
ISO 22000
WHO-GMP
HALAL

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